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Selective sensing of Al3+ ions by nitrophenyl induced coordination: imaging in zebrafish brain tissue

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Abstract

A p-nitrophenyl based rhodamine probe (NPRB) has been designed and synthesized for the selective, real-time detection of Al(III) in aqueous medium with a lower micromolar range detection limit at physiological pH. All the spectroscopic and theoretical analyses validated the proposed 1 : 1 complexation between NPRB and Al3+ along with an 80-fold enhancement in fluorescence intensity. Using the “turn on” response of the probe, binding of NPRB to Al3+ in the brain tissue of adult male zebrafish (D. rerio) has been visualized through fluorescence microscopy.

Graphical abstract: Selective sensing of Al3+ ions by nitrophenyl induced coordination: imaging in zebrafish brain tissue

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Publication details

The article was received on 23 Feb 2019, accepted on 08 Apr 2019 and first published on 09 Apr 2019


Article type: Communication
DOI: 10.1039/C9OB00460B
Org. Biomol. Chem., 2019, Advance Article

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    Selective sensing of Al3+ ions by nitrophenyl induced coordination: imaging in zebrafish brain tissue

    S. Das, U. Mukherjee, S. Pal, S. Maitra and P. Sahoo, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C9OB00460B

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