Mengjun Qiao, Jinli Zhang, Ling Chen, Fengyi Zhou, Yali Zhang, Lingfei Zhou and Yangjie Wu
Org. Biomol. Chem., 2019,17, 3790-3796
DOI:
10.1039/C9OB00336C,
Paper
A metal-free approach to N-aryl thioamides from Bunte salts and anilines in DMSO has been developed. This method tolerated a wide range of functional groups on the aromatic ring, providing an ideal way to N-aryl thioamides in good to excellent yields from cheap and easily available starting materials. A plausible mechanism was also proposed based on the X-ray single crystal diffraction, NMR and MS analyses of DMSO-concerning intermediates.
