Mengchen Yang, Chen Chen, Xing Yi, Yuan Li, Xiaoqin Wu, Qingshan Li and Shurong Ban
Org. Biomol. Chem., 2019,17, 2883-2886
DOI:
10.1039/C9OB00330D,
Communication
New chiral thiosquaramides and their applications in catalytic asymmetric double addition of 5-methyl-2(3H)-furanones to nitroolefins were described. Enantiomerically enriched 2,4,4-trisubstituted butenolides bearing a quaternary stereogenic center could be smoothly constructed with high diastereoselectivities (up to >99 : 1 dr) and excellent enantioselectivities (up to 95% ee) under mild conditions.