Tao Guo, Chuan-Chuan Wang, Xiang-Heng Fu, Yu Liu and Pan-Ke Zhang
Org. Biomol. Chem., 2019,17, 3333-3337
DOI:
10.1039/C9OB00294D,
Communication
An effective copper-catalyzed direct C–H/N–H cross-coupling of quinoxalin-2(1H)-ones with diverse unprotected 2-quinoxalinones and 2-quinolinones has been developed. This protocol provides a convenient route, with broad substrate scope, good functional group tolerance, and high atom economy, to various important quinoxalin-2(1H)-one-containing biheteroaryls, which are privileged structures in many biologically active compounds.
