Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S–H/N–H

Abstract

A practical and scalable electrochemical oxidation of S–H and N–H was developed. This oxidant- and catalyst-free electrochemical process enables S–N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.