Jump to main content
Jump to site search

Issue 12, 2019
Previous Article Next Article

Catalytic enantioselective iodolactonization reactions

Author affiliations

Abstract

The halolactonization reaction is a useful chemical transformation for the construction of lactones from γ- or δ-substituted alkenoic carboxylic acids or carboxylic esters. Traditionally, the stereoselectivity of these reactions has been controlled by the substrates or the reagents. The substrate-controlled method has been extensively studied and applied in the synthesis of many natural products. However, catalytic, enantioselective iodolactonizations of γ- or δ-substituted alkenoic carboxylic acids have only recently been developed. This review article highlights the advances that have emerged over the last decade.

Graphical abstract: Catalytic enantioselective iodolactonization reactions

Back to tab navigation

Publication details

The article was received on 20 Dec 2018, accepted on 19 Feb 2019 and first published on 19 Feb 2019


Article type: Review Article
DOI: 10.1039/C8OB03160F
Org. Biomol. Chem., 2019,17, 3079-3092

  •   Request permissions

    Catalytic enantioselective iodolactonization reactions

    R. Kristianslund, J. E. Tungen and T. V. Hansen, Org. Biomol. Chem., 2019, 17, 3079
    DOI: 10.1039/C8OB03160F

Search articles by author

Spotlight

Advertisements