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Issue 6, 2019
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Supramolecular vesicles based on pillar[n]arenes: design, construction, and applications

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Abstract

Supramolecular vesicles have attracted considerable attention due to their advantages of facile construction, high-cargo-loading capacity, and good biocompatibility. Pillar[n]arenes are a unique family of supramolecular macrocycles, exhibiting excellent features and broad applications due to their intrinsic topology and high functionality. In the past decade, the construction of pillar[n]arene-based supramolecular vesicles has been continuously attempted and developed rapidly. In this review, we mainly summarize the significant advancements of such supramolecular vesicles in the last three years. By showing some representative examples, the design strategies, construction methods, and potential applications of these dynamic nanocarriers are discussed in detail. In particular, the responsiveness of such vesicles to various external stimuli and their applications in drug delivery are highlighted. The outstanding performance of pillar[n]arene-based supramolecular vesicles would definitely enrich the family of supramolecular vesicles and promote the development of dynamic supramolecular materials.

Graphical abstract: Supramolecular vesicles based on pillar[n]arenes: design, construction, and applications

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Article information


Submitted
13 Dec 2018
Accepted
07 Jan 2019
First published
08 Jan 2019

Org. Biomol. Chem., 2019,17, 1336-1350
Article type
Review Article

Supramolecular vesicles based on pillar[n]arenes: design, construction, and applications

T. Xiao, W. Zhong, L. Xu, X. Sun, X. Hu and L. Wang, Org. Biomol. Chem., 2019, 17, 1336
DOI: 10.1039/C8OB03095B

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