Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.



Metal-free aza-Claisen type ring expansion of vinyl aziridines: an expeditious synthesis of seven membered N-heterocycles

Author affiliations

Abstract

A metal-free approach for the synthesis of 7-membered aza-heterocycles has been developed by the intermolecular [5 + 2] cycloaddition of non-activated vinylaziridines and alkynes. This method has a broad substrate scope under mild reaction conditions to afford structurally diverse 7-membered N-heterocycles in high yield up to 92%.

Graphical abstract: Metal-free aza-Claisen type ring expansion of vinyl aziridines: an expeditious synthesis of seven membered N-heterocycles

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Dec 2018, accepted on 04 Jan 2019 and first published on 05 Jan 2019


Article type: Communication
DOI: 10.1039/C8OB03029D
Citation: Org. Biomol. Chem., 2019, Advance Article

  •   Request permissions

    Metal-free aza-Claisen type ring expansion of vinyl aziridines: an expeditious synthesis of seven membered N-heterocycles

    D. Singh and H. Ha, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB03029D

Search articles by author

Spotlight

Advertisements