Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

Abstract

In recent years, a renewal of interest was shown to the quest for new synthetic solutions to directly introduce emergent fluorinated groups (SR_f) onto molecules. In this context, a new generation of reagents (ArSO₂SR_f) as efficient sources of SCF₃, SCF₂H and more generally SR_f groups, was designed. Hence, potent solutions were developed for the synthesis of SR_f-containing molecules, compounds of interest for drug and agrochemical research. This review highlights the recent advances made in the synthesis and the use of this new class of reagents, considerably extending the portfolio of tools for the direct introduction of SR_f moieties.