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Issue 7, 2019
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Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

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Abstract

In recent years, a renewal of interest was shown to the quest for new synthetic solutions to directly introduce emergent fluorinated groups (SRf) onto molecules. In this context, a new generation of reagents (ArSO2SRf) as efficient sources of SCF3, SCF2H and more generally SRf groups, was designed. Hence, potent solutions were developed for the synthesis of SRf-containing molecules, compounds of interest for drug and agrochemical research. This review highlights the recent advances made in the synthesis and the use of this new class of reagents, considerably extending the portfolio of tools for the direct introduction of SRf moieties.

Graphical abstract: Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

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Article information


Submitted
01 Dec 2018
Accepted
03 Jan 2019
First published
03 Jan 2019

Org. Biomol. Chem., 2019,17, 1683-1693
Article type
Review Article

Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

X. Pannecoucke and T. Besset, Org. Biomol. Chem., 2019, 17, 1683
DOI: 10.1039/C8OB02995D

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