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Issue 7, 2019
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Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

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Abstract

In recent years, a renewal of interest was shown to the quest for new synthetic solutions to directly introduce emergent fluorinated groups (SRf) onto molecules. In this context, a new generation of reagents (ArSO2SRf) as efficient sources of SCF3, SCF2H and more generally SRf groups, was designed. Hence, potent solutions were developed for the synthesis of SRf-containing molecules, compounds of interest for drug and agrochemical research. This review highlights the recent advances made in the synthesis and the use of this new class of reagents, considerably extending the portfolio of tools for the direct introduction of SRf moieties.

Graphical abstract: Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

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Publication details

The article was received on 01 Dec 2018, accepted on 03 Jan 2019 and first published on 03 Jan 2019


Article type: Review Article
DOI: 10.1039/C8OB02995D
Org. Biomol. Chem., 2019,17, 1683-1693

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    Use of ArSO2SRf reagents: an efficient tool for the introduction of SRf moieties

    X. Pannecoucke and T. Besset, Org. Biomol. Chem., 2019, 17, 1683
    DOI: 10.1039/C8OB02995D

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