Jump to main content
Jump to site search


TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines

Author affiliations

Abstract

A simple, practical and metal-free method has been developed for the synthesis of sulfonamides and β-arylsulfonyl enamines via the selective cleavage of C–N and C–H bonds through the iodine-catalyzed oxidation of arenesulfonyl chlorides and sodium sulfinates with tert-amines. The method uses commercially available inexpensive catalysts and oxidants, and has a wide substrate scope and operational simplicity.

Graphical abstract: TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Dec 2018, accepted on 07 Feb 2019 and first published on 07 Feb 2019


Article type: Paper
DOI: 10.1039/C8OB02992J
Citation: Org. Biomol. Chem., 2019, Advance Article

  •   Request permissions

    TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines

    H. Jiang, X. Tang, Z. Xu, H. Wang, K. Han, X. Yang, Y. Zhou, Y. Feng, X. Yu and Q. Gui, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB02992J

Search articles by author

Spotlight

Advertisements