Jump to main content
Jump to site search


Saturated Bioisosteres of Benzene: Where to go Next?

Abstract

The replacement of para-substituted benzenes with the saturated bioisosteres increases the potency, selectivity and metabolic stability of bioactive compounds. The current challenge for chemists is to rationally design, synthesize and validate the saturated bioisosteres for ortho- and meta-substituted benzenes.

Back to tab navigation

Publication details

The article was received on 11 Nov 2018, accepted on 10 Jan 2019 and first published on 10 Jan 2019


Article type: Review Article
DOI: 10.1039/C8OB02812E
Citation: Org. Biomol. Chem., 2019, Accepted Manuscript
  •   Request permissions

    Saturated Bioisosteres of Benzene: Where to go Next?

    P. K. Mykhailiuk, Org. Biomol. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C8OB02812E

Search articles by author

Spotlight

Advertisements