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Biosynthesis of bioactive natural products from Basidiomycota

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Abstract

The Basidiomycota, also called club fungi, comprise a diverse group of fungi. Basidiomycota are strongly related to ecosystem functioning along with human life. These fungi display a wide range of bioactivities, and some are known to produce of deadly toxins or hallucinogens. Some Basidiomycota have be used as medicinal mushrooms for thousands of years. Recently, the biosyntheses of several classes of natural products from Basidiomycota have been reported. Here, we review recent studies on the biosynthetic pathways and enzymes of bioactive natural products from Basidiomycota fungi, with a focus on terpenoids, alkaloids, ribosomally synthesized and post-translationally modified peptides (RiPPs), and polyketides.

Graphical abstract: Biosynthesis of bioactive natural products from Basidiomycota

  • This article is part of the themed collection: Biosynthesis
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Publication details

The article was received on 07 Nov 2018, accepted on 13 Dec 2018 and first published on 14 Dec 2018


Article type: Review Article
DOI: 10.1039/C8OB02774A
Citation: Org. Biomol. Chem., 2019, Advance Article
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    Biosynthesis of bioactive natural products from Basidiomycota

    H. Lin, R. T. Hewage, Y. Lu and Y. Chooi, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB02774A

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