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Fluorogenic probes for super-resolution microscopy

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Abstract

Fluorogenic probes efficiently reduce non-specific background signals, which often results in highly improved signal-to-noise ratios. Although this implies improved resolution, fluorogenic probes in the context of super-resolution microscopy are somewhat overlooked. Several excellent reviews summarize recent developments in SRM techniques, labeling techniques or different aspects of small synthetic fluorophores, however there is no comprehensive review on fluorogenic probes suitable for super-resolution microscopy. Herein we wish to fill this gap by providing the readers with an up-to-date summary of fluorogenic probes applied to super-resolution imaging of cellular structures.

Graphical abstract: Fluorogenic probes for super-resolution microscopy

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Publication details

The article was received on 31 Oct 2018, accepted on 03 Dec 2018 and first published on 04 Dec 2018


Article type: Review Article
DOI: 10.1039/C8OB02711K
Citation: Org. Biomol. Chem., 2019, Advance Article
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    Fluorogenic probes for super-resolution microscopy

    E. Kozma and P. Kele, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB02711K

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