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Issue 7, 2019
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Photoinduced decarboxylative azidation of cyclic amino acids

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Abstract

The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

Graphical abstract: Photoinduced decarboxylative azidation of cyclic amino acids

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Publication details

The article was received on 31 Oct 2018, accepted on 13 Dec 2018 and first published on 26 Dec 2018


Article type: Communication
DOI: 10.1039/C8OB02702A
Org. Biomol. Chem., 2019,17, 1839-1842

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    Photoinduced decarboxylative azidation of cyclic amino acids

    D. C. Marcote, R. Street-Jeakings, E. Dauncey, J. J. Douglas, A. Ruffoni and D. Leonori, Org. Biomol. Chem., 2019, 17, 1839
    DOI: 10.1039/C8OB02702A

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