Jump to main content
Jump to site search


Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition

Author affiliations

Abstract

The site-specific introduction of spin labels into RNA for distance measurements by EPR gives insight into its solution structure. We here present a method for spin labeling of in vitro transcribed RNA. Distance distributions between two nitroxide spin labels are determined by PELDOR in a self-complementary RNA duplex.

Graphical abstract: Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Oct 2018, accepted on 27 Nov 2018 and first published on 28 Nov 2018


Article type: Communication
DOI: 10.1039/C8OB02597E
Citation: Org. Biomol. Chem., 2019, Advance Article
  •   Request permissions

    Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition

    C. Domnick, G. Hagelueken, F. Eggert, O. Schiemann and S. Kath-Schorr, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB02597E

Search articles by author

Spotlight

Advertisements