Tian Qin, Quanbin Jiang, Jieying Ji, Jie Luo and Xiaodan Zhao
Org. Biomol. Chem., 2019,17, 1763-1766
DOI:
10.1039/C8OB02575D,
Communication
Chiral selenide-catalyzed enantioselective trifluoromethylthiolation of 1,1-disubstituted alkenes is disclosed. By this method, a variety of chiral trifluoromethylthiolated 2,5-disubstituted oxazolines were obtained in good yields with high enantioselectivities. This work not only provides a new pathway for the synthesis of chiral oxazolines, but also expands the library of chiral trifluoromethylthiolated molecules.