Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.

Issue 7, 2019
Previous Article Next Article

Synthesis of the core structure of phalarine

Author affiliations


The core skeleton of phalarine was rapidly synthesised through novel palladium-catalysed dearomative spirocyclisation and a palladium-catalysed Wacker-carbonylative cyclisation cascade. The two key steps allowed for the efficient construction of a tricyclic propeller skeleton bearing contiguous tetrasubstituted carbon centres, within 3 steps from a topologically planar precursor.

Graphical abstract: Synthesis of the core structure of phalarine

Back to tab navigation

Supplementary files

Article information

19 Sep 2018
29 Sep 2018
First published
01 Oct 2018

Org. Biomol. Chem., 2019,17, 1727-1730
Article type
Author version available

Synthesis of the core structure of phalarine

K. Douki, J. Shimokawa and M. Kitamura, Org. Biomol. Chem., 2019, 17, 1727
DOI: 10.1039/C8OB02320D

Social activity

Search articles by author