Issue 7, 2019

Total synthesis of incargranine A


Synthetic studies into the origins of the alkaloid incargranine A have resulted in the development of a four-step (longest linear sequence) total synthesis. This synthesis has been scaled-up to provide gram-scale quantities of material, which would alternatively require extraction of several metric-tons of dried-whole Chinese Trumpet-Creeper plants (Incarvillea mairei var. grandiflora).

Graphical abstract: Total synthesis of incargranine A

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Article information

Article type
22 Mar 2018
04 Apr 2018
First published
04 Apr 2018
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2019,17, 1698-1702

Total synthesis of incargranine A

P. D. Brown and A. L. Lawrence, Org. Biomol. Chem., 2019, 17, 1698 DOI: 10.1039/C8OB00702K

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