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2D DNA lattice arrays assembled from DNA dumbbell tiles using poly(A-T)-rich stems

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Abstract

Poly(A-T)-rich sequences have been applied as stems of DNA dumbbell tiles for construction of single crystalline 2D DNA lattice arrays in slightly acidic solutions. These arrays show much higher stability and better organised crystalline lattice structures than those assembled from DNA dumbbell tiles with randomly sequenced stems in slightly alkaline environments. DNA nanotechnology probably provides a useful platform to study the mechanical properties of DNA duplexes with specific sequences.

Graphical abstract: 2D DNA lattice arrays assembled from DNA dumbbell tiles using poly(A-T)-rich stems

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Publication details

The article was received on 14 Sep 2019, accepted on 30 Oct 2019 and first published on 31 Oct 2019


Article type: Communication
DOI: 10.1039/C9NR07911D
Nanoscale, 2019, Advance Article

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    2D DNA lattice arrays assembled from DNA dumbbell tiles using poly(A-T)-rich stems

    M. Ali, N. Afshan, C. Jiang, H. Zheng and S. Xiao, Nanoscale, 2019, Advance Article , DOI: 10.1039/C9NR07911D

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