Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Multifunctional and Flexible ZrO2-Coated EGaIn Nanoparticles for Photothermal Therapy


With the intensive study of liquid metals (LMs), Ga-based LMs attract more attention of biomedical researches for good biocompatibility, ideal fluidity and high thermal conductivity. The concern of liquid metal (LM) applied in cancer treatment is the high surface tension to form unstable nanoparticles. Here, ZrO2 is coated on the LM nanoparticles to form a stable core-shell nanostructure. In particular, the LM nanoparticles coated with ZrO2 and modified by PEG (LM@pZrO2 NPs) still maintain favorable flexibility, which is beneficial for cellular uptake. With the photothermal properties of LM, LM@pZrO2 NPs rapidly warm up and emit amount of heat under NIR laser radiation. It is confirmed that LM@pZrO2 NPs are more effectively internalized by cells and are beneficial to tumor photothermal therapy. This research provides a coating strategy to construct a stable and flexible core-shell LM nanostructure, making it a promising vehicle for nanotheranostics.

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Mar 2019, accepted on 03 May 2019 and first published on 06 May 2019

Article type: Communication
DOI: 10.1039/C9NR01963D
Nanoscale, 2019, Accepted Manuscript

  •   Request permissions

    Multifunctional and Flexible ZrO2-Coated EGaIn Nanoparticles for Photothermal Therapy

    N. Xia, N. Li, W. Rao, J. Yu, Q. Wu, L. Tan, H. Li, L. Gou, P. Liang, L. Li and X. Meng, Nanoscale, 2019, Accepted Manuscript , DOI: 10.1039/C9NR01963D

Search articles by author