Glucose Regulation by Modified Boronic Acid-Sulfobetaine Zwitterionic Nanogels - A Non-Hormonal Strategy for the Potential Treatment of Hyperglycemia
We have introduced a non-hormonal hyperglycemia treatment strategy by using an injectable glucose-responsive boronic acid- zwitterionic nanogel. The synthesized system, similar to an artificial liver, is capable of storing/releasing glucose at high/low blood glucose concentrations. In vivo performance revealed that the injection of the nanogels can effectively regulate the blood glucose in type 1 diabetic rats for at least 6 hours.
- This article is part of the themed collection: 2019 Nanoscale HOT Article Collection