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Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

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Abstract

Activated carbon nanodots functionalized with acid anhydride groups (AA-CNDs) are prepared by one-pot water-free green thermolysis of citric acid. As a proof of concept of their capabilities as appealing and versatile platforms for accessing engineering nanoconstructs, the as-prepared AA-CNDs have been reacted to yield clickable CNDs. Their click bioconjugation with relevant recognizable complementary clickable sugars has led to multivalent CND-based glyconanoparticles that are non-toxic and biorecognizable. The accessibility and intrinsic reactivity of AA-CNDs expand the current toolbox of covalent surface grafting methodologies and provide a wide range of potential applications for engineering (bio)nanoconstructs.

Graphical abstract: Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

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Publication details

The article was received on 22 Nov 2018, accepted on 15 Mar 2019 and first published on 20 Mar 2019


Article type: Paper
DOI: 10.1039/C8NR09459D
Citation: Nanoscale, 2019, Advance Article

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    Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

    M. Ortega-Muñoz, P. Vargas-Navarro, F. Hernandez-Mateo, A. Salinas-Castillo, L. F. Capitan-Vallvey, S. Plesselova, R. Salto-Gonzalez, M. D. Giron-Gonzalez, F. J. Lopez-Jaramillo and F. Santoyo-Gonzalez, Nanoscale, 2019, Advance Article , DOI: 10.1039/C8NR09459D

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