Issue 16, 2019

Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

Abstract

Activated carbon nanodots functionalized with acid anhydride groups (AA-CNDs) are prepared by one-pot water-free green thermolysis of citric acid. As a proof of concept of their capabilities as appealing and versatile platforms for accessing engineering nanoconstructs, the as-prepared AA-CNDs have been reacted to yield clickable CNDs. Their click bioconjugation with relevant recognizable complementary clickable sugars has led to multivalent CND-based glyconanoparticles that are non-toxic and biorecognizable. The accessibility and intrinsic reactivity of AA-CNDs expand the current toolbox of covalent surface grafting methodologies and provide a wide range of potential applications for engineering (bio)nanoconstructs.

Graphical abstract: Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

Supplementary files

Article information

Article type
Paper
Submitted
22 Nov 2018
Accepted
15 Mar 2019
First published
20 Mar 2019

Nanoscale, 2019,11, 7850-7856

Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs

M. Ortega-Muñoz, P. Vargas-Navarro, F. Hernandez-Mateo, A. Salinas-Castillo, L. F. Capitan-Vallvey, S. Plesselova, R. Salto-Gonzalez, M. D. Giron-Gonzalez, F. J. Lopez-Jaramillo and F. Santoyo-Gonzalez, Nanoscale, 2019, 11, 7850 DOI: 10.1039/C8NR09459D

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