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Issue 2, 2019
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DNA-free directed assembly in single-molecule cut-and-paste

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Abstract

Single-molecule cut-and-paste facilitates bottom-up directed assembly of nanoscale biomolecular networks in defined geometries and enables analysis with spatio-temporal resolution. However, arrangement of diverse molecules of interest requires versatile handling systems. The novel DNA-free, genetically encodable scheme described here utilises an orthogonal handling strategy to promote arrangement of enzymes and enzyme networks.

Graphical abstract: DNA-free directed assembly in single-molecule cut-and-paste

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Publication details

The article was received on 25 Oct 2018, accepted on 01 Dec 2018 and first published on 17 Dec 2018


Article type: Communication
DOI: 10.1039/C8NR08636B
Citation: Nanoscale, 2019,11, 407-411

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    DNA-free directed assembly in single-molecule cut-and-paste

    K. R. Erlich, S. M. Sedlak, M. A. Jobst, L. F. Milles and H. E. Gaub, Nanoscale, 2019, 11, 407
    DOI: 10.1039/C8NR08636B

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