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Cell factory engineering for improved production of natural products

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Abstract

Natural product biosynthesis is inherently linked with the primary metabolism in terms of providing precursors and co-factors. Thus, even though it is important to improve the performance of natural product biosynthetic enzymes in building efficient cell factories, it is equally important to engineer the central carbon metabolism, such that this is adjusted to meet the biosynthetic demand of the desired product.

Graphical abstract: Cell factory engineering for improved production of natural products

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Publication details

The article was received on 28 Jan 2019 and first published on 18 Apr 2019


Article type: Viewpoint
DOI: 10.1039/C9NP00005D
Nat. Prod. Rep., 2019, Advance Article
  • Open access: Creative Commons BY-NC license
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    Cell factory engineering for improved production of natural products

    J. Nielsen, Nat. Prod. Rep., 2019, Advance Article , DOI: 10.1039/C9NP00005D

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