Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 11, 2019
Previous Article Next Article

Catalytic asymmetric dearomatization (CADA) reaction-enabled total synthesis of indole-based natural products

Author affiliations

Abstract

Covering: 2000 up to 2019.

Catalytic asymmetric dearomatization (CADA) reactions have witnessed considerable development in recent years. As the most extensively studied sub-branch, asymmetric dearomatization reactions of indole derivatives have attracted particular interest from the synthetic organic community since the molecular complexity can be rapidly enhanced with this method and the asymmetric total synthesis of a series of alkaloid natural products may be achieved with this strategy. In this review, we present the recent contributions in this dynamic area. The synthetic details are documented according to their different dearomative cyclization strategies.

Graphical abstract: Catalytic asymmetric dearomatization (CADA) reaction-enabled total synthesis of indole-based natural products

Back to tab navigation

Article information


Submitted
22 Dec 2018
First published
06 Mar 2019

Nat. Prod. Rep., 2019,36, 1589-1605
Article type
Review Article

Catalytic asymmetric dearomatization (CADA) reaction-enabled total synthesis of indole-based natural products

C. Zheng and S. You, Nat. Prod. Rep., 2019, 36, 1589
DOI: 10.1039/C8NP00098K

Social activity

Search articles by author

Spotlight

Advertisements