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Issue 3, 2019
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Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

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Abstract

Covering: up to 2018

Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and various synthetic approaches to the preparation of tryptophol and its derivatives. Syntheses of various naturally occurring tryptophol derivatives known for their enhanced pharmacological profile are also presented.

Graphical abstract: Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

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Publication details

The article was received on 05 Apr 2018 and first published on 19 Sep 2018


Article type: Review Article
DOI: 10.1039/C8NP00032H
Citation: Nat. Prod. Rep., 2019,36, 490-530

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    Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

    A. Palmieri and M. Petrini, Nat. Prod. Rep., 2019, 36, 490
    DOI: 10.1039/C8NP00032H

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