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TiO2-SnS2 nanocomposite as novel matrix for development of enzymatic electrochemical glucose biosensor

Abstract

Titanium dioxide functionalized SnS2 nanocomposite was synthesized for the immobilization of glucose oxidase (GOx) to develop an enzymatic electrochemical glucose biosensor. Scanning electron microscope, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopic (XPS) spectrum and cyclic voltammetry were used to characterize the nanocomposite and the glucose biosensor. The TiO2-SnS2 composite shows a larger surface area and GOx entrapped in this matrix maintains excellent bioactivity and stability. The constructed glucose biosensor responds to glucose linearly over two concentration ranges of 0.008 to 1.13 mM and 1.13 to 5.53 mM at a working potential of -0.45 V. The biosensor exhibits a high sensitivity (18.9 mA M-1 cm - 2), low detection limit (1.8×10-6 M) and good repeatability. The present biosensor has excellent selectivity and can be successfully applied in detection of glucose in the serum samples. The advantages of the glucose biosensor shows that TiO2-SnS2 nanocomposite provides a new avenue for immobilizing proteins and fabricating excellent biosensors.

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Publication details

The article was received on 09 Sep 2019, accepted on 08 Oct 2019 and first published on 09 Oct 2019


Article type: Paper
DOI: 10.1039/C9NJ04629A
New J. Chem., 2019, Accepted Manuscript

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    TiO2-SnS2 nanocomposite as novel matrix for development of enzymatic electrochemical glucose biosensor

    Z. Yang, P. Yao, S. Yu, H. Shen, J. Yang, L. Min and X. Zhu, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ04629A

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