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Tracking mitochondrial viscosity in living systems based on a two-photon and near red probe

Abstract

A two-photon fluorescent probe Mito-V was designed for sensing the viscosity changes of mitochondria. The fluorescence emission at 634 nm increased about 22-fold from methanol to 99% glycerol indicating high viscosity dependence. Notably, in virtue of the probe, the mitochondria viscosity fluctuations have been successfully monitored not only in living cells but also in zebra fish and living mice.

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Publication details

The article was received on 18 Jul 2019, accepted on 16 Sep 2019 and first published on 04 Oct 2019


Article type: Paper
DOI: 10.1039/C9NJ03744F
New J. Chem., 2019, Accepted Manuscript

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    Tracking mitochondrial viscosity in living systems based on a two-photon and near red probe

    M. Peng, J. Yin and W. Lin, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ03744F

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