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The properties of the sonochemically functionalized nonsteroidal anti-inflammatory drug ketorolac in an Fe3O4–graphene oxide nanocomposite

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Abstract

Metallodrugs are in clinical use for the treatment of some diseases. A feasible sonochemical method is described for the complexation of the nonsteroidal anti-inflammatory drug, ketorolac, with an Fe3O4–graphene oxide nanocomposite. The extraction of ketorolac from this nanocomposite was studied in aqueous solutions at pH = 1, 5 and 8, imitating the gastrointestinal medium.

Graphical abstract: The properties of the sonochemically functionalized nonsteroidal anti-inflammatory drug ketorolac in an Fe3O4–graphene oxide nanocomposite

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Publication details

The article was received on 17 Jul 2019, accepted on 24 Sep 2019 and first published on 26 Sep 2019


Article type: Letter
DOI: 10.1039/C9NJ03730F
New J. Chem., 2019, Advance Article

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    The properties of the sonochemically functionalized nonsteroidal anti-inflammatory drug ketorolac in an Fe3O4–graphene oxide nanocomposite

    U. Fiadosenka, A. Matsukovich, L. Tabulina, V. Labunov and D. Radziuk, New J. Chem., 2019, Advance Article , DOI: 10.1039/C9NJ03730F

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