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Ruthenium catalyzed chemo and site-selective C–H amidation of oxobenzoxazine derivatives with sulfonyl azides

Abstract

An efficient, novel and general protocol towards the synthesis of highly functionalized ortho-amido oxobenzoxazine frameworks via ruthenium catalyzed intermolecular C–H amidation using sulfonyl azides as amidation component has been successfully developed for the first time. The salient features of this strategy are high chemo and site-selectivity, wide range of substrate scope with excellent yields and good functional group tolerance.

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Publication details

The article was received on 12 May 2019, accepted on 11 Aug 2019 and first published on 14 Aug 2019


Article type: Paper
DOI: 10.1039/C9NJ02452B
New J. Chem., 2019, Accepted Manuscript

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    Ruthenium catalyzed chemo and site-selective C–H amidation of oxobenzoxazine derivatives with sulfonyl azides

    M. Bakthadoss, P. Vijaya Kumar, R. Kumar, M. Surendar and S. S. duddu, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ02452B

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