Jump to main content
Jump to site search


Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

Author affiliations

Abstract

A stable primary-alkyl-substituted selenenic acid was developed as a synthetic model of selenocysteine–derived selenenic acid (Sec–SeOH) by taking advantage of a huge cavity-shaped substituent. The primary-alkyl model compound was successfully applied to model studies on the trapping reaction of protein Sec–SeOH generated in the active site of selenoenzymes with several reagents.

Graphical abstract: Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

Back to tab navigation

Supplementary files

Publication details

The article was received on 28 Feb 2019, accepted on 18 Mar 2019 and first published on 18 Mar 2019


Article type: Letter
DOI: 10.1039/C9NJ01072F
Citation: New J. Chem., 2019, Advance Article

  •   Request permissions

    Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

    S. Sase, R. Kimura, R. Masuda and K. Goto, New J. Chem., 2019, Advance Article , DOI: 10.1039/C9NJ01072F

Search articles by author

Spotlight

Advertisements