Organoselenium Small Molecules as Catalysts for Oxidative Functionalization of Organic Molecules
Although the fact that organoselenium chemistry has become an exciting topic in synthetic chemistry and pharmaceuticals from the last few decades. Usually, organoselenium molecules as reagents have only recently been developed in epoxidation or halogenation of olefins by using peroxides and dihalogens or halogenating reagents, respectively. Early few years, there are some reports are available but these are not a clear vision for catalytic use of organoselenium molecules and although important breakthroughs, they signify just the very preliminary stages of a nascent field. This perspective highlights the critical analysis of the challenges that lead to the development of organoselenium compounds and their use as a versatile catalyst in organic synthesis towards oxidation of olefins and C–H bonds in past one decade. Furthermore, the emphasis here differs from previous reviews of the field by classifying the various types of catalysis and the diverse strategies employed not only for oxidation of olefins but also carbon-hydrogen bond for carbon-carbon and carbon-heteroatom bond formation for the synthesis of various heterocyclic molecules by asymmetric indication.
- This article is part of the themed collection: Selenium & Tellurium chemistry at the beginning of the 3rd millennium: a celebration of ICCST