Jump to main content
Jump to site search


Electrochemical aptasensor based on potassium ion-triggered DNA conformation transition and self-assembly on electrode

Abstract

Herein, a novel electrochemical biosensor for sensitive and selective detection of potassium ion (K+) is developed. Aptamer sequence against K+ is integrated in a DNA probe for specific recognition, which initiates DNA conformation transition and activates thiol group for effective self-assembly of the DNA probe on gold electrode surface. By analyzing electrochemical signals labelled on the DNA probe, K+ level can be facilely determined. The proposed electrochemical aptasensor has plain sensing principle and simple operation. Moreover, excellent analytical performances are achieved owing to the ingenious design, which may also inspire the development of the other electrochemical biosensors.

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Jan 2019, accepted on 11 Apr 2019 and first published on 11 Apr 2019


Article type: Letter
DOI: 10.1039/C9NJ00158A
Citation: New J. Chem., 2019, Accepted Manuscript

  •   Request permissions

    Electrochemical aptasensor based on potassium ion-triggered DNA conformation transition and self-assembly on electrode

    H. Chai, X. Ma, F. Meng, Q. Mei, Y. Tang and P. Miao, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ00158A

Search articles by author

Spotlight

Advertisements