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Synthesis of artemisinin derived glycoconjugates inspired by click chemistry

Abstract

Herein we describe a synthesis of artemisinin based glycoconjugates (9a-i) by employing Cu(I)-catalysed reaction between β-propargylated dihydroartemisinin (7a) and azido sugars (8a-i) in moderate to excellent yields. Our synthesized artemisinin based glycoconjugates (9a-i) could prove to be an interesting class of bioactive molecules for the study of their various biological activities.

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Publication details

The article was received on 12 Nov 2018, accepted on 11 Feb 2019 and first published on 11 Feb 2019


Article type: Letter
DOI: 10.1039/C8NJ05737K
Citation: New J. Chem., 2019, Accepted Manuscript

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    Synthesis of artemisinin derived glycoconjugates inspired by click chemistry

    L. Goswami, S. Paul, T. K. Kotammagari and A. K. Bhattacharya, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C8NJ05737K

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