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Microwave-assisted Synthesis, Characterization, Cell Imaging of Fluorescent Carbon Dots Using L-Asparagine as Precursor

Abstract

L-asparagine, a common amino acid, is an economic and ideal precursor for carbon dots because its high nitrogen content, and its abundance in nature. By using L-asparagine as a biocompatible precursor, fluorescent nitrogen-doped carbon dots (A-CDs) were fast prepared by a one-pot microwave-assisted method. Then, a reasonable structure of A-CDs was put forward, which confirmed the accessibility that unconjugated small molecules could transform into carbon dots with sp2 core, and was helpful for the discussion of photoluminescence mechanism. What’s more, we concluded that the photoluminescence origin of A-CDs was from graphite-like structure and surface defects. Besides, the A-CDs showed a high stability in strong ionic solutions, and negligible cytotoxicity even the incubation concentration was up to 800 μg/mL. Finally, long-time bioimaging test suggested that A-CDs had great potential in a wide variety of biological applications.

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Publication details

The article was received on 25 Oct 2018, accepted on 08 Jan 2019 and first published on 09 Jan 2019


Article type: Paper
DOI: 10.1039/C8NJ05421E
Citation: New J. Chem., 2019, Accepted Manuscript
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    Microwave-assisted Synthesis, Characterization, Cell Imaging of Fluorescent Carbon Dots Using L-Asparagine as Precursor

    X. Wang, T. Gao, M. Yang, J. Zhao, F. Jiang and Y. Liu, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C8NJ05421E

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