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Issue 5, 2019
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Recent advances in functional nanomaterials for photoacoustic imaging of glioma

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Abstract

Glioma is a malignant tumor in the central nervous system with poor prognosis, high risk of recurrence and mortality. As the primary choice of treatment for glioma, surgery cannot effectively remove glioma cells owing to the lack of advanced intraoperative navigation technology. Photoacoustic (PA) imaging, a hybrid imaging technique, integrates the merits of optical and ultrasound imaging, exhibiting great potential for cancer surgery navigation. To enhance the sensitivity and specificity for visualizing the tumor margin, abundant contrast agents have been developed for enhanced PA imaging. In this minireview, we expect to draw attention to the recent advances in constructing functional nanomaterials as PA contrast agents for glioma imaging. The design and preparation of organic and inorganic nanomaterials for glioma PA imaging are discussed in detail. Meanwhile, the current challenges and perspectives of contrast-enhanced PA imaging of glioma are presented.

Graphical abstract: Recent advances in functional nanomaterials for photoacoustic imaging of glioma

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Publication details

The article was received on 20 May 2019, accepted on 07 Jun 2019 and first published on 07 Jun 2019


Article type: Minireview
DOI: 10.1039/C9NH00328B
Nanoscale Horiz., 2019,4, 1037-1045

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    Recent advances in functional nanomaterials for photoacoustic imaging of glioma

    D. Gao, D. Hu, X. Liu, Z. Sheng and H. Zheng, Nanoscale Horiz., 2019, 4, 1037
    DOI: 10.1039/C9NH00328B

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