Jump to main content
Jump to site search


Spatial Focusing of Magnetic Particle Hyperthermia

Abstract

Magnetic particle hyperthermia is a promising cancer therapy, but a typical constraint of its applicability is to localize heat solely to malignant regions sparing healthy surrounding tissues. By simultaneous application of a constant magnetic field together with the hyperthermia inducing alternating magnetic field, heating focus may be confined in smaller regions in a tunable manner. The main objective of this work is to evaluate the focusing parameters, by adequate selection of magnetic nanoparticles and field conditions and explore spatially focused magnetic particle hyperthermia efficiency in tissue phantom systems comprising of agarose gel and magnetic nanoparticles. Our results suggest the possibility of spatially-focused heating efficiency of magnetic nanoparticles through the application of a constant magnetic field. Tuning of the constant magnetic field parameters may result to minimizing thermal shock in surrounding regions without affecting the beneficiary thermal outcome in the focusing region.

Back to tab navigation

Publication details

The article was received on 21 Oct 2019, accepted on 24 Nov 2019 and first published on 25 Nov 2019


Article type: Paper
DOI: 10.1039/C9NA00667B
Nanoscale Adv., 2019, Accepted Manuscript
  • Open access: Creative Commons BY-NC license
  •   Request permissions

    Spatial Focusing of Magnetic Particle Hyperthermia

    E. Myrovali, N. Maniotis, T. Samaras and M. Angelakeris, Nanoscale Adv., 2019, Accepted Manuscript , DOI: 10.1039/C9NA00667B

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements