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Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations

Abstract

The facile formation of drug nanoparticles in injectible/ingestible oils, of the water-soluble antiretroviral tenofovir disproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.

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Publication details

The article was received on 23 Aug 2019, accepted on 07 Oct 2019 and first published on 12 Oct 2019


Article type: Communication
DOI: 10.1039/C9NA00529C
Nanoscale Adv., 2019, Accepted Manuscript
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    Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations

    J. Hobson, P. Curley, A. C. Savage, A. Al-khouja, M. Siccardi, C. Flexner, C. L. Freel Meyers, A. Owen and S. Rannard, Nanoscale Adv., 2019, Accepted Manuscript , DOI: 10.1039/C9NA00529C

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