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Carbon-based nanomaterials as an emerging platform for theranostics

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Abstract

Carbon-based nanomaterials include fullerenes, carbon nanotubes, graphene and its derivatives, graphene oxide, nanodiamonds, and carbon-based quantum dots. Due to their unique structural dimensions and excellent mechanical, electrical, thermal, optical and chemical properties, these materials have attracted significant interest in diverse areas, including biomedical applications. Among them, there has been recent focus on the imaging of cells and tissues and the delivery of therapeutic molecules for disease treatment and tissue repair. The broad-range one-photon property of carbon based-nanomaterials together with their biocompatibility and ease of functionalization has made them candidate imaging agents for tumor diagnosis. In particular, the intrinsic two-photon fluorescence property of carbon based-nanomaterials in the long wavelength region (near-infrared II) allows deep-tissue optical imaging. This review highlights the recent development on carbon based-nanomaterials in the field of one-photon and two-photon imaging and discusses their possible and promising diagnostic and therapeutic applications for the treatment of various diseases including cancer.

Graphical abstract: Carbon-based nanomaterials as an emerging platform for theranostics

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Publication details

The article was received on 13 Aug 2018, accepted on 21 Dec 2018 and first published on 21 Dec 2018


Article type: Review Article
DOI: 10.1039/C8MH00966J
Citation: Mater. Horiz., 2019, Advance Article
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    Carbon-based nanomaterials as an emerging platform for theranostics

    K. D. Patel, R. K. Singh and H. Kim, Mater. Horiz., 2019, Advance Article , DOI: 10.1039/C8MH00966J

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