Protein biomaterials for theranostic applications

Abstract

Protein biomaterials have been used for a wide range biomedical applications due to their intrinsic biocompatibility, versatility and higher order structure. Multifunctional theranostic agents fabricated by incorporating the diagnostic modalities and drug payloads in protein nanoformulations have garnered significant attention in recent years. Protein-based theranostic agents manifest high target specificity, enhanced blood circulation and reduce reticuloendothelial system elimination. This review focuses on the fabrication of peptide- and protein-based nanoformulations for imaging guided therapy.