Jump to main content
Jump to site search

Issue 23, 2019
Previous Article Next Article

Origami-paper-based device for microvesicle/exosome preconcentration and isolation

Author affiliations

Abstract

Microvesicles and exosomes are promising liquid biopsy biomarkers. However, conventional isolation techniques damage and contaminate the biomarkers. We developed an origami-paper-based device for effective isolation of biomarkers with less damage and in fewer steps. The multi-folded device enables the preconcentration of the microvesicles/exosomes on specific layers (∼5-fold) by the ion concentration polarization technique and they were simply isolated from the rest of the sample by unfolding the device.

Graphical abstract: Origami-paper-based device for microvesicle/exosome preconcentration and isolation

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Aug 2019, accepted on 18 Oct 2019 and first published on 18 Oct 2019


Article type: Communication
DOI: 10.1039/C9LC00796B
Lab Chip, 2019,19, 3917-3921

  •   Request permissions

    Origami-paper-based device for microvesicle/exosome preconcentration and isolation

    H. Kim, K. H. Lee, S. I. Han, D. Lee, S. Chung, D. Lee and J. H. Lee, Lab Chip, 2019, 19, 3917
    DOI: 10.1039/C9LC00796B

Search articles by author

Spotlight

Advertisements