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Issue 20, 2019
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Synthesis of rutaecarpine alkaloids via an electrochemical cross dehydrogenation coupling reaction

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Abstract

Substrates are directly oxidized at the anode without using any metal catalyst and oxidant to obtain a series of nitrogen heterocyclic compounds, including benzimidazoles and quinolinones. These compounds are highly tolerant to various functional groups and heterocycle-containing substrates. In addition, natural alkaloids, such as rutaecarpine and deoxyvasicinone, can be synthesized by this method.

Graphical abstract: Synthesis of rutaecarpine alkaloids via an electrochemical cross dehydrogenation coupling reaction

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Publication details

The article was received on 28 Aug 2019, accepted on 16 Sep 2019 and first published on 17 Sep 2019


Article type: Communication
DOI: 10.1039/C9GC03028J
Green Chem., 2019,21, 5517-5520

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    Synthesis of rutaecarpine alkaloids via an electrochemical cross dehydrogenation coupling reaction

    Q. Li, S. Cheng, H. Tang and Y. Pan, Green Chem., 2019, 21, 5517
    DOI: 10.1039/C9GC03028J

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