Jump to main content
Jump to site search


Strecker reactions with hexacyanoferrates as non-toxic cyanide sources

Author affiliations

Abstract

The Strecker reaction is the most widely applied three-component reaction. Although highly useful for the preparation of α-amino nitriles, α-amino acids, hydantoins and numerous related compounds, the need for the application of toxic sources of HCN limits its application in both academic and industrial settings. Here, we present a facile protocol for Strecker reactions using a mixture of potassium ferri- and ferrocyanides as a non-toxic substitute.

Graphical abstract: Strecker reactions with hexacyanoferrates as non-toxic cyanide sources

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Feb 2019, accepted on 22 Mar 2019 and first published on 22 Mar 2019


Article type: Paper
DOI: 10.1039/C9GC00720B
Citation: Green Chem., 2019, Advance Article

  •   Request permissions

    Strecker reactions with hexacyanoferrates as non-toxic cyanide sources

    C. Grundke and T. Opatz, Green Chem., 2019, Advance Article , DOI: 10.1039/C9GC00720B

Search articles by author

Spotlight

Advertisements