Jump to main content
Jump to site search


Rhodium(I)-catalyzed Pauson-Khand-type reaction using formic acid as a CO surrogate: an alternative approach for indirect CO2 utilization

Abstract

Formic acid is found to be an ideal CO surrogate for the rhodium-catalyzed Pauson-Khand-type (PK-type) reaction of various substituted 1,6-enynes to afford bicyclic cyclopentenones in moderate to good yields. High TON value up to 263 and nice results in gram scale experiment were also obtained, demonstrating the efficaciousness of this methodology. In addition, heterocyclic molecules of pharmaceutical importance were also furnished via inter- or intramolecular hetero-PK-type reactions, further broadening the application of current strategy. In this protocol, formic acid can be regarded as a bridging molecule from CO2 to CO, since formic acid is manufactured via catalytic hydrogenation of CO2 and releases CO in the presence of acetic anhydride readily. Therefore, this methodology represents a green and indirect approach for chemical valorization of CO2 in the preparation of value-added compounds.

Back to tab navigation

Supplementary files

Publication details

The article was accepted on 11 Jan 2019 and first published on 11 Jan 2019


Article type: Communication
DOI: 10.1039/C8GC03933J
Citation: Green Chem., 2019, Accepted Manuscript
  •   Request permissions

    Rhodium(I)-catalyzed Pauson-Khand-type reaction using formic acid as a CO surrogate: an alternative approach for indirect CO2 utilization

    X. Lang, F. You, X. He, Y. Yu and L. He, Green Chem., 2019, Accepted Manuscript , DOI: 10.1039/C8GC03933J

Search articles by author

Spotlight

Advertisements