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Effects of extruded whole-grain sorghum (Sorghum bicolor (L) Moench) based diets on calcium absorption and bone health of growing Wistar rats

Abstract

Calcium apparent absorption, total bone mineral content and density, and right femur minerals were studied using a growing rat model. Twenty-four male Wistar rats were fed with diets based on extruded whole grain red (RSD) or white sorghum (WSD), and control diet (CD) up to 60 days. The animals fed with sorghum diets consumed less diet and gained less weight than those of CD, but the efficiency of all diets was similar. Calcium intake was lower in animals fed with sorghum diets, related to the lower total intake of these animals. Calcium apparent absorption from RSD was lower than CD (CD:72.7%, RSD:51.0%, WSD:64.8%). No significant differences in bone mineral density of total body, spin, femur, distal femur, tibia and proximal tibia among groups were observed. However, Ca and P content of right femur of rats consuming RSD was lower indicating a certain imbalance in the metabolism of these minerals.

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Publication details

The article was received on 08 Aug 2019, accepted on 01 Nov 2019 and first published on 04 Nov 2019


Article type: Paper
DOI: 10.1039/C9FO01817D
Food Funct., 2019, Accepted Manuscript

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    Effects of extruded whole-grain sorghum (Sorghum bicolor (L) Moench) based diets on calcium absorption and bone health of growing Wistar rats

    M. G. G. Galán, A. Weisstaub, A. Zuleta and S. R. Drago, Food Funct., 2019, Accepted Manuscript , DOI: 10.1039/C9FO01817D

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