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Issue 4, 2019
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Caffeine release and absorption from caffeinated gums

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Abstract

The objectives of this study were to estimate the impact of chewing time on caffeine release from gum and to understand caffeine pharmacokinetics. Caffeine release increased with chewing time (2 min < 5 min < 10 min). Furthermore, two plasma caffeine concentration peaks were observed suggesting that caffeine absorption occurs both through the oral mucosa and gastrointestinal tract. This is of practical relevance to maximise caffeine doses and to synchronise effort with peak caffeine concentration.

Graphical abstract: Caffeine release and absorption from caffeinated gums

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Publication details

The article was received on 28 Feb 2019, accepted on 19 Mar 2019 and first published on 22 Mar 2019


Article type: Communication
DOI: 10.1039/C9FO00431A
Citation: Food Funct., 2019,10, 1792-1796

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    Caffeine release and absorption from caffeinated gums

    C. Morris, S. M. Viriot, Q. U. A. Farooq Mirza, G. A. Morris and A. Lynn, Food Funct., 2019, 10, 1792
    DOI: 10.1039/C9FO00431A

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