Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 1, 2019
Previous Article Next Article

Lactulose synergizes with CpG-ODN to modulate epithelial and immune cells cross talk

Author affiliations

Abstract

Lactulose, a non-digestible oligosaccharide and functional food, promotes Bifidobacteria growth. Here we show that lactulose, beyond its prebiotic action, may have direct immunomodulatory effects as well. In synergy with CpG-ODN, a bacterial DNA mimetic, lactulose enhances basolateral concentrations of IFN-γ, IL-10, and galectin-9 in the co-culture model of epithelial and immune cells.

Graphical abstract: Lactulose synergizes with CpG-ODN to modulate epithelial and immune cells cross talk

Back to tab navigation

Publication details

The article was received on 02 Dec 2018, accepted on 18 Dec 2018 and first published on 04 Jan 2019


Article type: Communication
DOI: 10.1039/C8FO02376J
Citation: Food Funct., 2019,10, 33-37

  •   Request permissions

    Lactulose synergizes with CpG-ODN to modulate epithelial and immune cells cross talk

    R. Mukherjee, M. van de. Kaa, J. Garssen, R. J. Pieters, A. D. Kraneveld and L. E. M. Willemsen, Food Funct., 2019, 10, 33
    DOI: 10.1039/C8FO02376J

Search articles by author

Spotlight

Advertisements