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A copper(II)–dipicolylamine–coumarin sensor for maltosyltransferase assay

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Abstract

A Cu(II)–[di(2-methylpyridyl)methylamino]coumarin fluorescence turn-on sensor (Cu-1b) is designed to detect phosphate ions with Kass = 1.4 × 105 M−1 in HEPES buffer. Cu-1b is applied to probe the GlgE-catalyzed maltose-transfer reaction of α-maltose-1-phosphate to α-1,4-glucan with concomitant release of phosphate ions in Mycobacterium tuberculosis.

Graphical abstract: A copper(ii)–dipicolylamine–coumarin sensor for maltosyltransferase assay

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Publication details

The article was received on 29 Mar 2019, accepted on 26 Apr 2019 and first published on 26 Apr 2019


Article type: Communication
DOI: 10.1039/C9DT01339C
Dalton Trans., 2019, Advance Article

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    A copper(II)–dipicolylamine–coumarin sensor for maltosyltransferase assay

    W. Lee, T. Hsu, W. Hung and J. Fang, Dalton Trans., 2019, Advance Article , DOI: 10.1039/C9DT01339C

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