Herein we designed and synthesized a cell penetrating peptide- and cancer-targeted molecule-functionalized multi-walled carbon nanotube for precise orthotopic glioma therapy. In addition to reduced toxicity, this nanosystem exhibited enhanced cancer recognition, blood–brain barrier (BBB) penetration, and anticancer activity through increased ROS production.
Y. You, N. Wang, L. He, C. Shi, D. Zhang, Y. Liu, L. Luo and T. Chen, Dalton Trans., 2019, 48, 1569 DOI: 10.1039/C8DT03948H
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